resveratrol references

Work in progress UNFINISHED - HYPOTHESIS

We should be looking at general principles of controlling zoonotic viruses and their sequelae.
We need much more research as we go into the future, because there will be many more global viruses like COVID-19.

COVID-19 problem

Hypothesis PMID(s) General Searches Notes
viral infections Resveratrol may inhibit replication of, or kill COVID-19 virus in vitro. (in a test tube in the lab.) Resveratrol may help control a great many viruses. 28193191
32228827
16875760
23776451
22391746
32228827
resveratrol+virus resveratrol  seems to have broad spectrum activity in many viruses due to
acute lung injury Unknown in COVID-19 but resveratrol in animal studies  may protect the integrity of respiratory  epithelium in non-coronavirus situations.. 30093935
29512867
29844304
28733146
27959278
25973008
24818579
sepsis Unknown in COVID-19 but resveratrol in animal studies  protects against multi-system and organ damage caused by LPS and similar bacterial toxins which have gotten into the bloodstream or other wrong parts of the body. 29240645
30588304
30994109
31282985
32093379
31389921
28646814
cytokine storm Unknown in COVID-19 but resveratrol in animal studies protects against multi-organ damage caused by LPS and similar. May interrupt causes of cytokine storm. 22646800 See this 2012 article for an  intro to the cytokine storm
pulmonary fibrosis Unknown in COVID-19 but resveratrol helps ameliorate pulmonary fibrosis in several other conditions 25515609
airway Unknown in COVID-19 resveratrol helps clear the airway in many conditions.
coronary function resveratrol protects the heart but activity in COVID-19 is unknown.
ARDS Unknown in COVID-19 26648661
neurological damage. Unknown in COVID-19 but RESV is broadly neuroprotective in many other situations. For example, in sepsis and spinal disc illness it prevents/helps/heals nerve damage

30150559

26924896

replicative senescence/immune system exhaustion

coagulopathy May be helpful in Kawasaki disease for example.

26947597

18928399

comorbid infections Like many serious viral infections do, COVID-19 may leave people vulnerable to acquiring many additional infections.
fungal infection resveratrol is antifungal in candida infections.

25413604

28971316

bacterial infection

Pubmed searches for source plant names (synonyms):
Polygonum cuspidatum
Fallopia japonica
Reynoutria japonica

And constituents:

Resveratrol
Emodin
Polydatin